The Effect of Ptz - Induced Seizures on Neuronal Damage in Amygdala of Rats
نویسندگان
چکیده
Dark neurons are seen in neurosurgical biopsies, experimental ischemia, hypoglycemia, and epilepsy. This study was aimed to investigate probable damage of amygdala due to pentylenetetrazol (PTZ) induced acute seizures in rat. Male Wistar rats were divided into control, sham, and PTZ groups. EEG recordings were performed before and after the PTZ injection in PTZ group. Dark neuron numbers in amygdala were compared. Dark neurons were seen in PTZ group; however, there was no significant difference between PTZ, control and sham groups. The result of present study showed that amygdala maybe damage in acute PTZ induced seizures.
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